Location: Albany, NY Category: Research Foundation Careers Posted On: Fri Aug 9 2024 Job Description:

Description of Duties:

UAlbany's Laboratory of Redox Biology and Signal Transduction, headed by Dr. Ben Boivin, is seeking to recruit one postdoctoral researcher. Research in our lab focuses on deciphering how redox modifications of proteins influence phosphorylation-dependent signal transduction in biology and pathologies. We strive to understand the link between the structure and the function of the Protein Tyrosine Phosphatase (PTP) family members that become turned off by oxidation to gain insight into redox signaling mechanisms underlying disease initiation and progression. We recently identified an approach to reactivate the oxidized and inactivated form of PTP1B (Londhe et al., 2020, Nature Chemical Biology), and showed that the oxidation and inactivation of PTP1B in the heart unleashes a thyroid-hormone dependent hypertrophic response and heart failure (Coulis et al., 2022, Science Signaling). In the position offered, the postdoctoral researcher will use their knowledge, and unpublished data from our lab, as a basis to explore how PTP1B becomes inactivated in cardiac hypertrophy and to apply novel therapeutic strategies to reactivate PTP1B in vivo. The candidate will learn and use biochemical, biophysical and molecular biology approaches (e.g. immunoblots, immunoprecipitations, microscopy, redox assays, proteomics, Flexcell, AAV-mediated gene-therapy, etc.) in vitro, in cardiomyocytes and using animal models. In this NIH-funded position, the successful candidate will have the opportunity to present their work at national and international meetings, to participate in collaborative projects and to be trained in successful grant writing.

Job Requirements:

Minimum Qualifications:

• PhD in Biochemistry or related field

• Motivated candidates with interests in cellular signaling and cardiac hypertrophy

• Demonstrated ability to perform, analyze, interpret and think critically about experiments in the context of a broader research project

• Candidates should have at least one published manuscript, or a manuscript currently on a preprint server

• Excellent communication and interpersonal skills to collaborate effectively within a multidisciplinary team

• Applicants must demonstrate an ability to develop inclusive and equitable relationships within our diverse campus community

• Applicants must demonstrate an ability to support diversity, equity, access, inclusion, and belonging, relative to their role

  Additional Information:

Salary: $61,000-$68,000

Federal law and regulations require notice to all prospective employees regarding crimes that have occurred on campus in the current three year period. Please refer to the following website for the complete Annual Security Report ("Clery Report"): http://police.albany.edu/asr.htm

As an Equal Opportunity/Affirmative Action Employer, The Research Foundation for SUNY will not discriminate in its employment practices due to an applicant's race, color, creed, religion, sex (including pregnancy, childbirth or related medical conditions), sexual orientation, gender identity or expression, transgender status, age, national origin, marital status, citizenship, physical and mental disability, criminal record, genetic information, predisposition or carrier status, status with respect to receiving public assistance, domestic violence victim status, a disabled, special, recently separated, active duty wartime, campaign badge, Armed Forces service medal veteran, or any other characteristics protected under applicable law.

The Research Foundation for The State University of New York offers exceptional benefits such as healthcare, dental, vision, pension plans, competitive pay, generous paid time off, tuition assistance, life insurance and long-term disability insurance. The University at Albany offers a variety of performing arts, world class libraries, and competitive sporting events.