Life Science Research Professional 1

School of Medicine, Stanford, California, United States

Research

Post Date Mar 27, 2024

Requisition # 102679

Stanford University is seeking a Life Science Research Professional 1 to perform basic functions and activities involved in defined research projects, and independently conduct and analyze experiments.

Stanford University is one of the world’s most renowned universities. Sitting in the heart of the San Francisco Bay Area among the valley’s most progressive companies.

You will be working with an unparalleled leading-edge community of faculty and staff that are fundamentally changing the world of health care. You will have the opportunity to influence and drive change with your innovative ideas, the ability to make a difference and participate in human advancements. Our culture is fast-paced, energetic, and growing all of the time.

We offer a variety of benefits beyond traditional medical, dental, retirement, and savings options:

• Events and program for children, sports camps, tuition options

• World-class intellectual stimulation through learning and development classes, workshops, and onsite conferences from leading-edge speakers and faculty

• Work/life and family-friendly policies and reimbursement

• Participation in Stanford’s social responsibility and sustainable programs for a better world

• A vibrant university culture that values the uniqueness of each individual

We are seeking candidates who are progressive thinkers, see challenges as simply problems to solve, and have the spirit and energy to change the world.

About the Department of Pathology:

Comprised of extraordinary faculty and staff, our mission is to improve the ability to diagnose, treat and understand the origin and manifestation of human disease, and to care for those who have or are at risk to develop disease. We accomplish this through our clinical services (in all fields of anatomic and clinical pathology, including molecular and genomic pathology, histocompatibility testing and transfusion medicine) and be research (which includes basic, translational and clinical research into the origins and manifestations of disease, including efforts to improve disease prediction and prevention as part of the goal of achieving precision medicine and health), and also by educating future leaders in pathology and related fields. Everything we do is to achieve the goals of providing the highest quality of clinical services to the patients for whom we passionately care, to advance our ability to understand, diagnose, monitor and ultimately to cure disease or to prevent or delay its occurrence, and to provide outstanding education and career development opportunities to those who share these goals.

For more information about the department visithttp://pathology.stanford.edu/

About the Lab:

Our laboratory seeks to maximize the diagnostic data potential from minimally invasive diagnostics using highly sensitive methylation platform technologies. We study the fundamental characteristics of and create quantitative models for cell-free nucleic acids (DNA) as a data-rich marker for medical diagnostics. We also have a tradition of engineering the necessary tools to digitize biological data from nucleic acids into digital data for eventual medical interpretation. For patients, this will eventually mean obtaining critical medical information the need for immediate surgeries or highly invasive procedures.

Current Interests:

Our research team recently invented a methylation sequencing profiler that enriches genome-wide by up to 16- fold (95%+ of reads have unbiased CpG data), and we are leveraging it on banked clinical specimens to focus on: tumor classification, early cancer detection, early cancer prognostication, enhancing minimally invasive biopsies classification and prognostication, and tools to advance the diagnostic resolution of hard-to-diagnose clinical cases.

More information about the lab can be found here: https://cfna.stanford.edu/

About the Job:

We are seeking a motivated Life Science Research Professional 1 to help support research in the minimally invasive testing field. Opportunities for independent work that can lead to a publication are available and encouraged. Skills learned can prepare the researcher for a future in graduate or professional school, or as a scientist/engineer in the growing multibillion dollar industry of cell-free DNA diagnostics. Funding is provided by NIH, Burroughs Welcome, and the Department of Pathology. The desired candidate is self-motivated, detail-oriented, independent, patient, punctual, and conscientious, with excellent written/oral communication and interpersonal skills. Under the supervision of the principal investigator, duties include participation in research projects, clinical study design and execution, assay development, NGS library preparation, data collection, and assistance with data analysis and manuscripts. There will be ample opportunities for publication.

Lab’s track record: Previous 3 LSRP1s got 1) 8 papers in 2 years, 2) first author poster and secondary authorship pending in a year, and 3) 1 co-authorship and secondary authorship pending in 2 years. All LSRP1s got into their graduate, medical, and CLS schools based on their original goals. Everyone gained skills in clinical studies, wet lab, automation, NGS sequencing, cfDNA testing, and informatics.

Duties include:

• Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory.

• Independently conduct experiments; maintain detailed records of experiments and outcomes. Perform informatic and statistical analysis on next generation sequencing and other molecular big data.

• Apply the theories and methods of a life science or quantitative discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.

• Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.

• Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.

• Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.

• Help with specimen procurement for clinical studies.

• Assist with orientation and training of new staff or students on lab procedures or techniques.

*- Other duties may also be assigned

Desired Qualifications:

• Bachelor’s degree in biochemistry, bioengineering, biology/genetics, computational biology, physics, chemistry or a related area;

• Knowledge and experience in the following fields: bioinformatics in relation to genomics or at least programming experience, molecular biology, biochemistry.

• Self-motivated, good communications and the ability to perform as part of a team.

Education & Experience (Required):

• Bachelor's degree in related scientific field.

Knowledge, Skills, and Abilities (Required):

• General understanding of scientific principles.

• Demonstrated performance to use knowledge and skills when needed.

• Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.

• Ability to maintain detailed records of experiments and outcomes.

• General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.

• Ability to work under deadlines with general guidance.

• Excellent organizational skills and demonstrated ability to accurately complete detailed work.

Physical Requirements*:

• Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.

• Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.

• Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.

• Must have correctible vision to perform duties of the job.

• Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.

• Ability to lift heavy objects weighing up to 50 pounds.

• Ability to work in a dusty, dirty, and odorous environment.

• Position may require repetitive motion.

*- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

Working Conditions:

• May require working in close proximity to blood borne pathogens.

• May require work in an environment where animals are used for teaching and research.

• Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.

• Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.

• May require extended or unusual work hours based on research requirements and business needs.

• Due to the nature of the work, this position will work fully on-site.

• This position will be located onsite at our Stanford location in Hillview, Palo Alto, CA.

The expected pay range for this position is $26.44 - $36.54 per hour.

Stanford University provides pay ranges representing its good faith estimate of what the university reasonably expects to pay for a position. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location and external market pay for comparable jobs.

At Stanford University, base pay represents only one aspect of the comprehensive rewards package. The Cardinal at Work website (https://cardinalatwork.stanford.edu/benefits-rewards) provides detailed information on Stanford’s extensive range of benefits and rewards offered to employees. Specifics about the rewards package for this position may be discussed during the hiring process.

Why Stanford is for You

Imagine a world without search engines or social platforms. Consider lives saved through first-ever organ transplants and research to cure illnesses. Stanford University has revolutionized the way we live and enrich the world. Supporting this mission is our diverse and dedicated 17,000 staff. We seek talent driven to impact the future of our legacy. Our culture and unique perks empower you with:

• Freedom to grow. We offer career development programs, tuition reimbursement, or course auditing. Join a TedTalk, film screening, or listen to a renowned author or global leader speak.

• A caring culture. We provide superb retirement plans, generous time-off, and family care resources.

• A healthier you. Climb our rock wall or choose from hundreds of health or fitness classes at our world-class exercise facilities. We also provide excellent health care benefits.

• Discovery and fun. Stroll through historic sculptures, trails, and museums.

• Enviable resources. Enjoy free commuter programs, ridesharing incentives, discounts and more

The job duties listed are typical examples of work performed by positions in this job classification and are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks, and responsibilities. Specific duties and responsibilities may vary depending on department or program needs without changing the general nature and scope of the job or level of responsibility. Employees may also perform other duties as assigned.

Consistent with its obligations under the law, the university will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

Stanford is an equal employment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

Additional Information

• Schedule: Full-time

• Job Code: 4943

• Employee Status: Fixed-Term

• Grade: E

• Requisition ID: 102679

• Work Arrangement : On Site